October 2010
2 posts
“Attending ICSB 2010: £435. Train ticket to Edinburgh: £58. Windows freezing...”
– Vangelis Simeonidis
August 2010
1 post
July 2010
1 post
“Professionally our methods of transmitting and reviewing the results of research...”
– Vannevar Bush, 1945
May 2010
2 posts
“Science publishing now is like transporting needles in huge bales of hay. There...”
– Jan Velterop
March 2010
1 post
“I can pretend to be a fission yeast and I can do it quite well”
– Sir Paul Nurse
November 2009
1 post
“Q: What is Ontology? A: It Depends on What the Meaning of “Is” Is.”
– Clay Shirky
August 2009
8 posts
Phylogenetic tree reconstruction
Shamil Sunyaev gives a great overview on the many different algorithms and tools for reconstruction of phylogenetic trees.
Global Mapping of Copy-Number Variants in Humans...
Jan Korbel gives a beautiful example of how even high-resolution maps can be flawed. This old map of the world is pretty accurate except from Australia being absent.
Guru Meditation #00000008.00000340
Opening slide from the symposium that takes place in conjunction with the EMBO World Practical Course in Shanghai.
Computational analysis of metagenomics data: basic...
Jeroen Raes giving an excellent summary of the many challenges in analysis of metagenomics data. In many cases statistically significant differences are do to “something else”: differences in sampling methods (e.g. filter sizes used for ocean samples), sequencing technologies (e.g. differences in read length), and sequence processing (e.g. algorithms used for assembly and gene...
Integration of external datasets with metagenomics...
Liping Zhao giving a very interesting introduction to how the gut microbiome interacts with the human body. Gut bacteria are not only crucial for performing metabolic processes in the gut but can also regulate the expression of metabolic proteins encoded by the human genome and thereby cause obesity.
Our beloved leader Peer Bork gives us priceless...
I wonder if his advice also applies to posting this photo ;-)
Impact of next-generation sequencing on mapping...
Jan Korbel presented the methods used for generating global maps of genomic structural variants in sequenced eukaryotic and bacterial genomes. He also touched upon the problem that computational biologists will soon need to deal with petabyte computation, which will require new approaches compared to how we work today.
The Sequencing R-Evolution: Traditional vs. Next...
Francesca Ciccarelli explaining the Sanger, Roche 454 pyrosequencing, Illumina Solexa reversible-terminator sequencing, ABI SOLiD sequencing by ligation, and Helicos single-molecule sequencing technologies. Each method has its strengths and weaknesses, but the new technologies are generally better suited for re-sequencing than for de novo sequencing due to their shorter read lengths....
July 2009
2 posts
April 2009
1 post
October 2008
2 posts
“It’s when you can’t explain things it’s fun, because you know...”
– Tim Hunt
“It is very important to know what you would like to know, what you think you...”
– Tim Hunt
July 2008
4 posts
“I am to old to compare my method to other methods by showing that we’re...”
– Phil Bourne
“It is rather easy to make a transition: you go back to being a postdoc, you find...”
– Gene Myers
“Despite large parametric uncertainty, small prediction uncertainties are still...”
– Christopher R. Myers
“Saying that an integer can go into a string and that they are thus interoperable...”
– Paul Gordon
June 2008
1 post
“No grand idea was ever born in a conference, but a lot of foolish ideas have...”
– F. Scott Fitzgerald