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Lars Juhl Jensen

Research professor in disease systems biology at the Novo Nordisk Foundation Center for Protein Research in Copenhagen. Co-founder of the company Intomics. My specialty is data and text mining.

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Sep
22nd
Tue
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Aug
24th
Mon
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Favor moves that increase options; shy away from moves that end well but require cutting off choices; work from strong positions that have many adjoining strong positions. Balance looking ahead to really paying attention to what’s happening now on the whole board.
— Kevin Kelly
Aug
21st
Fri
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Metagenomic methods for gut bacterial genomics and biofuel production

Jian Xu presenting approaches to use meta-genomics, -transcriptomics, and -metabolomics for studying the gut microbiota as well as organisms useful for the production of biofuels.

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Toward Automatic Reconstruction of a Highly Resolved Tree of Life

Francesca Ciccarelli gives a short presentation of how a unified tree
of life was constructed based on concatenated protein alignments.

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The impact of Orthology, Paralogy and Homology assignments

Roland Krause explains how to identify orthologous genes and why it is important to discriminate between orthologs and homologs.

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Phylogenetic tree reconstruction

Shamil Sunyaev gives a great overview on the many different algorithms and tools for reconstruction of phylogenetic trees.

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Estimation of Genomic Instability with Ultradeep Sequencing

Francesca Ciccarelli presents a new database called “Network of Cancer Genes” that contains information on the evolution and interactions of cancer genes (http://bio.ifom-ieo-campus.it/ncg/).

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Global Mapping of Copy-Number Variants in Humans by Next-Generation Sequencing

Jan Korbel gives a beautiful example of how even high-resolution maps can be flawed. This old map of the world is pretty accurate except from Australia being absent.

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Bridging from molecular simulation to biochemical networks

Rebecca Wade explaining how molecular simulations can be used to estimate parameters needed for modeling of biological systems.

Aug
20th
Thu
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Learning about rates and mechanisms of mutations from functional genomics

Shamil Sunyaev asking the question that I think many researchers should ask themselves more often: why bother?